Prostaglandin E1 for preventing the progress of pulmonary arterial hypertension in rat model
Pulmonary artery hypertension (PAH) is a progressive chronic disease with a high mortality rate.Increased pulmonary vascular resistance and over-proliferation of pulmonary Ball - Catcher - Body Pad artery endothelial cells lead to remodeling of pulmonary vasculature.Several anti-PAH therapies targeting various pathways involved in PAH progression h